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1

Integrated Disinfection By-Products Mixtures Research: Comprehensive Characterization of Water Concentrates Prepared from Chlorinated and Ozonated/Postchlorinated Drinking Water

Richardson, Susan D., Thruston, Alfred D., Krasner, Stuart W., Weinberg, Howard S., Miltner, Richard J., Schenck, Kathleen M., Narotsky, Michael G., McKague, A. Bruce, Simmons, Jane Ellen

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 440 KB

english, 2008

2

Integrated Disinfection By-Products Mixtures Research: Concentration by Reverse Osmosis Membrane Techniques of Disinfection By-Products from Water Disinfected by Chlorination and Ozonation/Postchlorination

Speth, Thomas F., Miltner, Richard J., Richardson, Susan D., Simmons, Jane Ellen

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 263 KB

english, 2008

3

Global optimization of the MichaelisâMenten parameters using physiologically-based pharmacokinetic (PBPK) modeling and chloroform vapor uptake data in F344 rats

Evans, Marina V., Eklund, Christopher R., Williams, David N., Sey, Yusupha M., Simmons, Jane Ellen

Journal:

Inhalation Toxicology

Year:

2020

Language:

english

File:

PDF, 2.47 MB

english, 2020

4

Mammalian cell cytotoxicity and genotoxicity of the haloacetic acids, a major class of drinking water disinfection by-products

Michael J. Plewa, Jane Ellen Simmons, Susan D. Richardson, Elizabeth D. Wagner

Journal:

Environmental and Molecular Mutagenesis

Year:

2010

Language:

english

File:

PDF, 185 KB

english, 2010

5

Ds-optimal designs for studying combinations of chemicals using multiple fixed-ratio ray experiments

Michelle Casey, Chris Gennings, W. Hans Carter Jr., Virginia C. Moser, Jane Ellen Simmons

Journal:

Year:

2005

Language:

english

File:

PDF, 161 KB

english, 2005

6

The differential hepatotoxicity and cytochrome P450 responses of fischer-344 rats to the three isomers of dichlorobenzene

John W. Allis, Jane Ellen Simmons, Dennis E. House, Barbara L. Robinson, Ezra Berman

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

1992

Language:

english

File:

PDF, 808 KB

english, 1992

7

Preface

Jane Ellen Simmons

Journal:

Year:

1995

Language:

english

File:

PDF, 55 KB

english, 1995

8

Methanol potentiation of carbon tetrachloride hepatotoxicity: The central role of cytochrome P450

John W. Allis, Barbara L. Brown, Jane Ellen Simmons, Gary E. Hatch, Anthony McDonald, Dennis E. House

Journal:

Year:

1996

Language:

english

File:

PDF, 987 KB

english, 1996

9

Power and Sample Size Calculations for Linear Hypotheses Associated with Mixtures of Many Components using Fixed-Ratio Ray Designs

Michelle Casey, Chris Gennings, W Hans Carter, Virginia C Moser, Jane Ellen Simmons

Journal:

Environmental and Ecological Statistics

Year:

2006

Language:

english

File:

PDF, 215 KB

english, 2006

10

Detecting Departure From Additivity Along a

Sharon D. Yeatts, Chris Gennings, Elizabeth D. Wagner, Jane Ellen Simmons, Michael J. Plewa

Journal:

Journal of Agricultural, Biological, and Environmental Statistics

Year:

2010

Language:

english

File:

PDF, 244 KB

english, 2010

11

Failure of carbon disulfide and levothyroxine to modify the cardiovascular response of rabbits to a high-cholesterol diet

Ethard W. Van Stee, Jane Ellen Simmons, Richard A. Sloane, Michael P. Moorman, Bernard Adkins Jr., Beverly Y. Cockrell

Journal:

Year:

1986

Language:

english

File:

PDF, 677 KB

english, 1986

12

Chemical mixtures: challenge for toxicology and risk assessment

Jane Ellen Simmons

Journal:

Year:

1995

Language:

english

File:

PDF, 954 KB

english, 1995

13

Duration Adjustment of Acute Exposure Guideline Level Values for Trichloroethylene Using a Physiologically-Based Pharmacokinetic Model

William K. Boyes, Marina V. Evans, Christopher Eklund, Paul Janssen, Jane Ellen Simmons

Journal:

Year:

2005

Language:

english

File:

PDF, 143 KB

english, 2005

14

Detecting interaction(s) and assessing the impact of component subsets in a chemical mixture using fixed-ratio mixture ray designs

Michelle Casey, Chris Gennings, W. Hans Carter, Virginia C. Moser, Jane Ellen Simmons

Journal:

Journal of Agricultural, Biological, and Environmental Statistics

Year:

2004

Language:

english

File:

PDF, 421 KB

english, 2004

15

The impact of exposure to a mixture of eighteen polyhalogenated aromatic hydrocarbons on thyroid function: Estimation of an interaction threshold

Chris Gennings, W. Hans Carter, Richard A. Carchman, Michael J. DeVito, Jane Ellen Simmons, Kevin M. Crofton

Journal:

Journal of Agricultural, Biological, and Environmental Statistics

Year:

2007

Language:

english

File:

PDF, 409 KB

english, 2007

16

Physiologically Based Pharmacokinetic Estimated Metabolic Constants and Hepatotoxicity of Carbon Tetrachloride after Methanol Pretreatment in Rats

Marina Villafañe Evans, Jane Ellen Simmons

Journal:

Toxicology and Applied Pharmacology

Year:

1996

Language:

english

File:

PDF, 179 KB

english, 1996

17

A pharmacokinetic model of anaerobic in vitro carbon tetrachloride metabolism

Nancy J. Andersen, Chris L. Waller, Joseph B. Adamovic, Daniel J. Thompson, John W. Allis, Melvin E. Andersen, Jane Ellen Simmons

Journal:

Chemico-Biological Interactions

Year:

1996

Language:

english

File:

PDF, 1.26 MB

english, 1996

18

Pregnancy loss and eye malformations in offspring of F344 rats following gestational exposure to mixtures of regulated trihalomethanes and haloacetic acids

Michael G. Narotsky, Deborah S. Best, Anthony McDonald, Elizabeth A. Godin, E. Sidney Hunter III, Jane Ellen Simmons

Journal:

Reproductive Toxicology

Year:

2011

Language:

english

File:

PDF, 178 KB

english, 2011

19

Improving the scientific foundation for mixtures joint toxicity and risk assessment: Contributions from the SOT mixtures project—Introduction

Ann M. Mason, Christopher J. Borgert, James S. Bus, M. Moiz Mumtaz, Jane Ellen Simmons, I. Glenn Sipes

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 126 KB

english, 2007

20

Identification of developmentally toxic drinking water disinfection byproducts and evaluation of data relevant to mode of action

Joan Colman, Glenn E. Rice, J. Michael Wright, E. Sidney Hunter III, Linda K. Teuschler, John C. Lipscomb, Richard C. Hertzberg, Jane Ellen Simmons, Margaret Fransen, Mark Osier, Michael G. Narotsky

Journal:

Toxicology and Applied Pharmacology

Year:

2011

Language:

english

File:

PDF, 617 KB

english, 2011

21

Dose-Dependent Vehicle Differences in the Acute Toxicity of Bromodichloromethane

Patrick D. Lilly, Jane Ellen Simmons, Rex A. Pegram

Journal:

Fundamental and Applied Toxicology

Year:

1994

File:

PDF, 486 KB

1994

22

Analysis of functional effects of a mixture of five pesticides using a ray design

Chris Gennings, W. Hans Carter Jr., Michelle Casey, Virginia Moser, Richard Carchman, Jane Ellen Simmons

Journal:

Environmental Toxicology and Pharmacology

Year:

2004

Language:

english

File:

PDF, 183 KB

english, 2004

23

Developing an exposure–dose–response model for the acute neurotoxicity of organic solvents: overview and progress on in vitro models and dosimetry

Philip J. Bushnell, Timothy J. Shafer, Ambuja S. Bale, William K. Boyes, Jane Ellen Simmons, Christopher Eklund, Trachette L. Jackson

Journal:

Environmental Toxicology and Pharmacology

Year:

2005

Language:

english

File:

PDF, 212 KB

english, 2005

24

EPA project-level research strategies for chemical mixtures: targeted research for meaningful results

Linda K. Teuschler, Richard C. Hertzberg, Glenn E. Rice, Jane Ellen Simmons

Journal:

Environmental Toxicology and Pharmacology

Year:

2004

Language:

english

File:

PDF, 398 KB

english, 2004

25

Applications of dosimetry modeling to assessment of neurotoxic risk

William K. Boyes, Jane Ellen Simmons, Christopher Eklund, Vernon A. Benignus, Paul Janssen, Philip J. Bushnell

Journal:

Environmental Toxicology and Pharmacology

Year:

2005

Language:

english

File:

PDF, 99 KB

english, 2005

26

Cholinesterase inhibition and depression of the photic after discharge of flash evoked potentials following acute or repeated exposures to a mixture of carbaryl and propoxur

Jean-Claude Mwanza, Danielle F. Lyke, Richard C. Hertzberg, Lynne Haber, Melissa Kohrman-Vincent, Ruosha Li, Yi Pan, Robert H. Lyles, Jane Ellen Simmons, Denise K. MacMillan, R. Dan Zehr, Adam E. Swan

Journal:

NeuroToxicology

Year:

2012

Language:

english

File:

PDF, 785 KB

english, 2012

27

Lethality and hepatotoxicity of complex waste mixtures

Jane Ellen Simmons, David M. DeMarini, Ezra Berman

Journal:

Environmental Research

Year:

1988

Language:

english

File:

PDF, 765 KB

english, 1988

28

Fasting for less than 24 h induces cytochrome P450 2E1 and 2B1/2 activities in rats

Barbara L. Brown, John W. Allis, Jane Ellen Simmons, Dennis E. House

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 597 KB

english, 1995

29

Effect of subchronic corn oil gavage on the acute toxicity of orally administered bromodichloromethane

Patrick D. Lilly, Jane Ellen Simmons, Rex A. Pegram

Journal:

Toxicology Letters

Year:

1996

Language:

english

File:

PDF, 855 KB

english, 1996

30

Testing for additivity in chemical mixtures using a fixed-ratio ray design and statistical equivalence testing methods

LeAnna G. Stork, Chris Gennings, Walter H. Carter, Robert E. Johnson, Darcy P. Mays, Jane Ellen Simmons, Elizabeth D. Wagner, Michael J. Plewa

Journal:

Journal of Agricultural, Biological, and Environmental Statistics

Year:

2007

Language:

english

File:

PDF, 348 KB

english, 2007

31

Mutagenicity in Salmonella of hazardous wastes and urine from rats fed these wastes

David M. DeMarini, Jefferson P. Inmon, Jane Ellen Simmons, Ezra Berman, Todd C. Pasley, Sarah H. Warren, Ronald W. Williams

Journal:

Mutation Research/Genetic Toxicology

Year:

1987

Language:

english

File:

PDF, 818 KB

english, 1987

32

Analysis of mixtures of drugs/chemicals along a fixed-ratio ray without single-chemical data to support an additivity model

Stephanie L. Meadows-Shropshire, Chris Gennings, W. Hans Carter, Jane Ellen Simmons

Journal:

Journal of Agricultural, Biological, and Environmental Statistics

Year:

2004

Language:

english

File:

PDF, 232 KB

english, 2004

33

Integrated Disinfection By-Products (DBP) Mixtures Research: Gene Expression Alterations in Primary Rat Hepatocyte Cultures Exposed to DBP Mixtures Formed by Chlorination and Ozonation/Postchlorination

Crosby, Lynn M., Simmons, Jane Ellen, Ward, William O., Moore, Tanya M., Morgan, Kevin T., DeAngelo, Anthony B.

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 289 KB

english, 2008

34

Integrated Disinfection By-Products Mixtures Research: Disinfection of Drinking Waters by Chlorination and Ozonation/Postchlorination Treatment Scenarios

Miltner, Richard J., Speth, Thomas F., Richardson, Susan D., Krasner, Stuart W., Weinberg, Howard S., Simmons, Jane Ellen

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 171 KB

english, 2008

35

Medical News.

DeMarini, David M., Gallagher, Jane E., Houk, Virginia S., Simmons, Jane Ellen

Journal:

Year:

1865

Language:

english

File:

PDF, 616 KB

english, 1865

36

TUBERCULOSIS SOCIETY.

DeMarini, David M., Gallagher, Jane E., Houk, Virginia S., Simmons, Jane Ellen

Journal:

Year:

1928

Language:

english

File:

PDF, 416 KB

english, 1928

37

Toxicological evaluation of complex industrial wastes: implications for exposure assessment

DeMarini, David M., Gallagher, Jane E., Houk, Virginia S., Simmons, Jane Ellen

Journal:

Toxicology Letters

Year:

1989

Language:

english

File:

PDF, 1.07 MB

english, 1989

38

Preface

Simmons, Jane Ellen

Journal:

Year:

2013

Language:

english

File:

PDF, 220 KB

english, 2013

39

Comparison of open and blind histopathologic evaluation of hepatic lesions

House, Dennis E., Berman, Ezra, Seely, John C., Simmons, Jane Ellen

Journal:

Toxicology Letters

Year:

1992

Language:

english

File:

PDF, 466 KB

english, 1992

40

A four-step approach to evaluate mixtures for consistency with dose addition

Hertzberg, Richard C., Pan, Yi, Li, Ruosha, Haber, Lynne T., Lyles, Robert H., Herr, David W., Moser, Virginia C., Simmons, Jane Ellen

Journal:

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

41

Supplement 6 || Development of a Research Strategy for Integrated Technology-Based Toxicological and Chemical Evaluation of Complex Mixtures of Drinking Water Disinfection Byproducts

Jane Ellen Simmons, Susan D. Richardson, Thomas F. Speth, Richard J. Miltner, Glenn Rice, Kathleen M. Schenck, E. Sidney Hunter, III and Linda K. Teuschler

Journal:

Environmental Health Perspectives

Year:

2002

Language:

english

File:

PDF, 3.35 MB

english, 2002

42

Supplement 2: Trichloroethylene Health Risks-State of the Science || Neurotoxic and Pharmacokinetic Responses to Trichloroethylene as a Function of Exposure Scenario

William K. Boyes, Philip J. Bushnell, Kevin M. Crofton, Marina Evans and Jane Ellen Simmons

Journal:

Environmental Health Perspectives

Year:

2000

Language:

english

File:

PDF, 1.43 MB

english, 2000

43

Integrated Chemical and Toxicological Investigation of UV-Chlorine/Chloramine Drinking Water Treatment

Lyon, Bonnie A., Milsk, Rebecca Y., DeAngelo, Anthony B., Simmons, Jane Ellen, Moyer, Mary P., Weinberg, Howard S.

Journal:

Environmental Science & Technology

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

44

Peer Reviewed: Disinfection Byproducts: The Next Generation

Richardson, Susan D., Simmons, Jane Ellen, Rice, Glenn

Journal:

Environmental Science & Technology

Year:

2002

Language:

english

File:

PDF, 75.19 MB

english, 2002

45

Immunotoxicologic Assessment of Subacute Exposure of Rats to Carbon Tetrachloride with Comparison to Hepatotoxicity and Nephrotoxicity

SMIALOWICZ, RALPH J., SIMMONS, JANE ELLEN, LUEBKE, ROBERT W., ALLIS, JOHN W.

Journal:

Toxicological Sciences

Year:

1991

Language:

english

File:

PDF, 1.67 MB

english, 1991

46

NOAEL AND LOAEL DETERMINATIONS OF ACUTE HEPATOTOXICITY FOR CHLOROFORM AND BROMODICHLOROMETHANE DELIVERED IN AN AQUEOUS VEHICLE TO F344 RATS

Thomas E. Keegan Jane Ellen Simmons,

Journal:

Journal of Toxicology and Environmental Health

Year:

1998

Language:

english

File:

PDF, 277 KB

english, 1998

47

Moving From External Exposure Concentration to Internal Dose: Duration Extrapolation Based on Physiologically Based Pharmacokinetic Derived Estimates of Internal Dose

Simmons, Jane Ellen, Evans, Marina V., Boyes, William K.

Journal:

Journal of Toxicology and Environmental Health

Year:

2005

Language:

english

File:

PDF, 166 KB

english, 2005

48

Research Issues Underlying the Four-Lab Study: Integrated Disinfection By-Products Mixtures Research

Simmons, Jane Ellen, Richardson, Susan D., Teuschler, Linda K., Miltner, Richard J., Speth, Thomas F., Schenck, Kathleen M., Hunter, E. Sidney, Rice, Glenn

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 114 KB

english, 2008

49

Hepatic and Renal Assessment of Acute Exposure to Inhaled Epichlorohydrin: Toxicological Evaluation and Exposure Modeling

Robinson, Barbara L., Guinnup, David E., Andrews, James E., Allis, John W., McDonald, Anthony, Seely, John C., Mohin, Timothy J., Simmons, Jane Ellen

Journal:

Inhalation Toxicology

Year:

1995

Language:

english

File:

PDF, 833 KB

english, 1995

50

Integrated Disinfection By-Products Research: Salmonella Mutagenicity of Water Concentrates Disinfected by Chlorination and Ozonation/Postchlorination

Claxton, Larry D., Pegram, Rex, Schenck, Kathleen M., Simmons, Jane Ellen, Warren, Sarah H.

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 232 KB

english, 2008

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